Pain relief medications, also known as analgesics, are drugs used to alleviate pain. These medications work by blocking or reducing the perception of pain in the body. Pain relief medications can be classified into different categories, including nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminophen, opioids, and others. The type of pain relief medication used depends on the severity of the pain and the underlying cause of the pain. Some pain relief medications are available over-the-counter, while others are only available by prescription from a doctor. Different painkillers work in different ways, and the choice of pain relief medication depends on the type, severity, and cause of the pain.